BodyTemperature & Fluid Laboratory
Waseda University

Research for our well-being
Waseda University Body temperature and Fluid laboratory



  • Uchida Y, Nagashima K, Yuri K. Fasting or systemic des-acyl ghrelin administration to rats facilitates thermoregulatory behavior in a cold environment. Brain Res. 2018 May 31. pii: S0006-8993(18)30302-0. doi: 10.1016/j.brainres.2018.05.038. [Epub ahead of print] PubMed PMID: 29859973.
  • Uchida Y, Onishi K, Tokizawa K, Nagashima K. Regional differences of cFos immunoreactive cells in the preoptic areas in hypothalamus associated with heat and cold responses in mice. Neurosci Lett. 2018 Feb 5;665:130-134. doi: 10.1016/j.neulet.2017.11.053. Epub 2017 Nov 26. PubMed PMID: 29183691.
  • Fujii N, Aoki-Murakami E, Tsuji B, Kenny GP, Nagashima K, Kondo N, Nishiyasu T. Body temperature and cold sensation during and following exercise under temperate room conditions in cold-sensitive young trained females. Physiol Rep. 2017 Nov;5(20). pii: e13465. doi: 10.14814/phy2.13465. PubMed PMID: 29061863; PubMed Central PMCID: PMC5661232.
  • Uchida Y, Nagashima K, Yuri K. Systemic estradiol administration to ovariectomized rats facilitates thermoregulatory behavior in a cold environment. Brain Res. 2017 Sep 1;1670:125-134. doi: 10.1016/j.brainres.2017.06.009. Epub 2017 Jun 9. PubMed PMID: 28602745.
  • Marui S, Misawa A, Tanaka Y, Nagashima K. Assessment of axillary temperature for the evaluation of normal body temperature of healthy young adults at rest in a thermoneutral environment. J Physiol Anthropol. 2017 Feb 22;36(1):18. doi: 10.1186/s40101-017-0133-y. PubMed PMID: 28228153; PubMed Central PMCID: PMC5322586.
  • Nagashima K. Thermal information from the skin: the signal processing and the role in behavioral thermoregulation. Temperature (Austin). 2015 Oct 12;2(3):334-5. doi: 10.1080/23328940.2015.1053597. eCollection 2015 Jul-Sep. PubMed PMID: 27227042; PubMed Central PMCID: PMC4843905.
  • Nagashima K. Thermoregulation and menstrual cycle. Temperature (Austin). 2015 Jul 15;2(3):320-1. doi: 10.1080/23328940.2015.1066926. eCollection 2015 Jul-Sep. PubMed PMID: 27227035; PubMed Central PMCID: PMC4843915.
  • Tokizawa K, Matsuda-Nakamura M, Tanaka Y, Uchida Y, Lin CH, Nagashima K. Influence of osmotic stress on thermal perception and thermoregulation in heat is different between sedentary and trained men. Physiol Behav. 2016 Jul 1;161:66-73. doi: 10.1016/j.physbeh.2016.04.018. Epub 2016 Apr 13. PubMed PMID: 27085909.
  • Sato N, Marui S, Ozaki M, Nagashima K. Cold exposure and/or fasting modulate the relationship between sleep and body temperature rhythms in mice. Physiol Behav. 2015 Oct 1;149:69-75. doi: 10.1016/j.physbeh.2015.05.024. Epub 2015 May 27. PubMed PMID: 26025785.
  • Tokizawa K, Yoda T, Uchida Y, Kanosue K, Nagashima K. Estimation of the core temperature control during ambient temperature changes and the influence of circadian rhythm and metabolic conditions in mice. J Therm Biol. 2015 Jul;51:47-54. doi: 10.1016/j.jtherbio.2015.03.005. Epub 2015 Mar 12. PubMed PMID: 25965017.
  • Matsuda-Nakamura M, Yasuhara S, Nagashima K. Effect of menstrual cycle on thermal perception and autonomic thermoregulatory responses during mild cold exposure. J Physiol Sci. 2015 Jul;65(4):339-47. doi: 10.1007/s12576-015-0371-x. Epub 2015 Mar 12. PubMed PMID: 25762225.
  • Uchida Y, Tokizawa K, Nagashima K. Characteristics of activated neurons in the suprachiasmatic nucleus when mice become hypothermic during fasting and cold exposure. Neurosci Lett. 2014 Sep 5;579:177-82. doi: 10.1016/j.neulet.2014.07.039. Epub 2014 Jul 30. PubMed PMID: 25083810.
  • Tokizawa K, Onoue Y, Uchida Y, Nagashima K. Ghrelin induces time-dependent modulation of thermoregulation in the cold. Chronobiol Int. 2012 Jul;29(6):736-46. doi: 10.3109/07420528.2012.678452. PubMed PMID: 22734574.
  • Nakamura M, Yoda T, Crawshaw LI, Kasuga M, Uchida Y, Tokizawa K, Nagashima K, Kanosue K. Relative importance of different surface regions for thermal comfort in humans. Eur J Appl Physiol. 2013 Jan;113(1):63-76. doi: 10.1007/s00421-012-2406-9. Epub 2012 May 9. PubMed PMID: 22569893.
  • Uchida Y, Tokizawa K, Nakamura M, Lin CH, Nagashima K. Tail position affects the body temperature of rats during cold exposure in a low-energy state. J Comp Physiol A Neuroethol Sens Neural Behav Physiol. 2012 Feb;198(2):89-95. doi: 10.1007/s00359-011-0690-1. Epub 2011 Oct 29. PubMed PMID: 22037912.
  • Uchida Y, Tokizawa K, Nakamura M, Mori H, Nagashima K. Estrogen in the medial preoptic nucleus of the hypothalamus modulates cold responses in female rats. Brain Res. 2010 Jun 21;1339:49-59. doi: 10.1016/j.brainres.2010.04.021. Epub 2010 Apr 21. PubMed PMID: 20416284.
  • Tokizawa K, Yasuhara S, Nakamura M, Uchida Y, Crawshaw LI, Nagashima K. Mild hypohydration induced by exercise in the heat attenuates autonomic thermoregulatory responses to the heat, but not thermal pleasantness in humans. Physiol Behav. 2010 Jun 16;100(4):340-5. doi: 10.1016/j.physbeh.2010.03.008. Epub 2010 Mar 15. PubMed PMID: 20298707.
  • Uchida Y, Kano M, Yasuhara S, Kobayashi A, Tokizawa K, Nagashima K. Estrogen modulates central and peripheral responses to cold in female rats. J Physiol Sci. 2010 Mar;60(2):151-60. doi: 10.1007/s12576-009-0079-x. Epub 2009 Dec 29. PubMed PMID: 20039154.
  • Kanosue K, Crawshaw LI, Nagashima K, Yoda T. Concepts to utilize in describing thermoregulation and neurophysiological evidence for how the system works. Eur J Appl Physiol. 2010 May;109(1):5-11. doi: 10.1007/s00421-009-1256-6. Epub 2009 Oct 31. Review. PubMed PMID: 19882166.
  • Tokizawa K, Uchida Y, Nagashima K. Thermoregulation in the cold changes depending on the time of day and feeding condition: physiological and anatomical analyses of involved circadian mechanisms. Neuroscience. 2009 Dec 15;164(3):1377-86. doi: 10.1016/j.neuroscience.2009.08.040. Epub 2009 Aug 22. PubMed PMID: 19703527.
  • Nakamura M, Yoda T, Crawshaw LI, Yasuhara S, Saito Y, Kasuga M, Nagashima K, Kanosue K. Regional differences in temperature sensation and thermal comfort in humans. J Appl Physiol (1985). 2008 Dec;105(6):1897-906. doi: 10.1152/japplphysiol.90466.2008. Epub 2008 Oct 9. PubMed PMID: 18845785.
  • Yoda T, Crawshaw LI, Saito K, Nakamura M, Nagashima K, Kanosue K. Effects of alcohol on autonomic responses and thermal sensation during cold exposure in humans. Alcohol. 2008 May;42(3):207-12. doi: 10.1016/j.alcohol.2008.01.006. PubMed PMID: 18420115.
  • Nakamura M, Esaki H, Yoda T, Yasuhara S, Kobayashi A, Konishi A, Osawa N, Nagashima K, Crawshaw LI, Kanosue K. A new system for the analysis of thermal judgments: multipoint measurements of skin temperatures and temperature-related sensations and their joint visualization. J Physiol Sci. 2006 Dec;56(6):459-64. Epub 2006 Nov 8. PubMed PMID: 17090339.
  • Nagashima K. Central mechanisms for thermoregulation in a hot environment. Ind Health. 2006 Jul;44(3):359-67. Review. PubMed PMID: 16922179.
  • Yoda T, Crawshaw LI, Nakamura M, Saito K, Konishi A, Nagashima K, Uchida S, Kanosue K. Effects of alcohol on thermoregulation during mild heat exposure in humans. Alcohol. 2005 Jul;36(3):195-200. PubMed PMID: 16377461.
  • Nagashima K, Matsue K, Konishi M, Iidaka C, Miyazaki K, Ishida N, Kanosue K. The involvement of Cry1 and Cry2 genes in the regulation of the circadian body temperature rhythm in mice. Am J Physiol Regul Integr Comp Physiol. 2005 Jan;288(1):R329-35. Epub 2004 Aug 26. PubMed PMID: 15331384.
  • Maruyama M, Nishi M, Konishi M, Takashige Y, Nagashima K, Kiyohara T, Kanosue K. Brain regions expressing Fos during thermoregulatory behavior in rats. Am J Physiol Regul Integr Comp Physiol. 2003 Nov;285(5):R1116-23. Epub 2003 Jul 31. PubMed PMID: 12893652.
  • /ul>


    第58回日本生気象学会大会 (相模原、相模女子大学)

    加藤一聖、増田雄太、丸井朱里、永島 計
    (早稲田大学 人間科学学術院 体温・体液研究室)
    増田雄太、丸井朱里、加藤一聖、永島 計
    (早稲田大学人間科学研究科 体温・体液研究室)
    唐木幸音、丸井朱里、永島 計
    (早稲田大学 人間科学学術院 体温・体液研究室)
    丸井朱里、永島 計
    早稲田大学人間科学学術院 体温・体液研究室)

    第74回日本体力医学会大会 (つくば)

    増田 雄太
    加藤 一聖
    丸井 朱里
    (早稲田大学人間科学部 体温・体液研究室 )


    増田雄太,丸井朱里, 加藤一聖, 永島計
    (早稲田大学 人間科学研究科 体温・体液研究室)
    (1早稲田大学 人間科学研究科 2早稲田大学 人間科学学術院 体温・体液研究室)
    丸井朱里,伊藤花歩, 永島計
    (早稲田大学 人間科学学術院 体温・体液研究室)

    第58日本生体医工学会大会 (沖縄)

    〇加藤 一聖 1), 増田 雄太 1), 丸井 朱里 2), 永島 計 2)
    1) 早稲田大学 人間科学研究科, 2) 早稲田大学 人間科学学術院

    WFATT 2019 WORLD CONGRESS (東京、幕張)

    Assessment of physical load during sports activities in junior high school students with wearable sensors
    Issei Kato
    Wearable accelerometer as a tool evaluating thermal load during running exercise
    Yuta Masuda

    9th FAOPS congress(神戸)

    Assessment of thermal load during exercise in junior high school students using wearable sensors
    Issei Kato1, Yuta Masuda1, Shuri Marui1, Kei Nagashima1
    1Department of Human science, University of waseda, Japan
    Estimation of basal body temperature from breast skin temperature during sleep
    Shuri Marui1, Kei Nagashima1
    1Faculty of Human Sciences, Waseda University, Japan
    The effect of environmental temperature on spontaneous exercise in mice
    Yuta Masuda1, Shuri Marui2, Ken Tokizawa3, Issei Kato1, Kei Nagashima2
    1Department of Human sciences, Waseda University, Japan
    2Faculty of Human Sciences, Waseda University, Japan
    3National Institute of Occupational Safety and Health, Japan






    増田 雄太
    永島 計


    (1早稲田大学 人間科学研究科 2早稲田大学 人間科学学術院)
    (1早稲田大学 人間科学研究科)
    丸井 朱里,永島 計
    (早稲田大学 人間科学学術院 体温・体液研究室)